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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDCD4 All Species: 28.79
Human Site: S68 Identified Species: 63.33
UniProt: Q53EL6 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q53EL6 NP_055271.2 469 51721 S68 R R L R K N S S R D S G R G D
Chimpanzee Pan troglodytes XP_001143474 469 51730 S68 R R L R K N S S R D S G R G D
Rhesus Macaque Macaca mulatta XP_001086788 469 51733 S68 R R L R K N S S R D S G R G D
Dog Lupus familis XP_535012 469 51702 S68 R R L R K N S S R D S G R G D
Cat Felis silvestris
Mouse Mus musculus Q61823 469 51684 S68 R R L R K N S S R D S G R G D
Rat Rattus norvegicus Q9JID1 469 51718 S68 R R L R K N S S R D S G R G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513214 469 51772 S68 R R L R K N S S R D S G R G D
Chicken Gallus gallus Q98TX3 467 51689 S66 K R R L R K N S S R D S G R G
Frog Xenopus laevis NP_001080530 455 50476 K54 K A Q R R L R K N S S R D S G
Zebra Danio Brachydanio rerio NP_945329 470 51893 N68 V K R R L R K N S S R D S G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781080 464 51309 R57 R I T K K A K R R L K R S P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98 98.2 N.A. 96.5 96.5 N.A. 93.1 84.8 73.7 69.7 N.A. N.A. N.A. N.A. 47.9
Protein Similarity: 100 100 99.5 99.5 N.A. 98.5 98.7 N.A. 97.8 93.1 86.9 83.8 N.A. N.A. N.A. N.A. 66.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 13.3 13.3 13.3 N.A. N.A. N.A. N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 33.3 26.6 26.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 64 10 10 10 0 64 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 64 10 73 19 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 19 10 0 10 73 10 19 10 0 0 10 0 0 0 0 % K
% Leu: 0 0 64 10 10 10 0 0 0 10 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 64 10 10 10 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 73 73 19 82 19 10 10 10 73 10 10 19 64 10 10 % R
% Ser: 0 0 0 0 0 0 64 73 19 19 73 10 19 10 10 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _